Cancer Poster Session
Discussion and Conclusion
The present study has clearly demonstrated that electrochemotherapy is an effective treatment for decreasing tumor volume of the metastatic lesion of hamster oral fibrosarcoma. Thus, in vivo, the local potentiation of CPA by the electrochemotherapy results in substantial anticancer acting even with the administration of small amounts of drug which limits side-effects. The effects of other anticancer drugs as well as their minimal effective dose with electric pulses should be further studied. In addition, efforts are under way to examine various routes of administration of the anticancer drugs and ways to increase the effectiveness of the therapy. The results from this experimental animal studies will be instrumental in using this treatment for the clinic.
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|Maeda, H; Kojima, A; Sugita, Y; Tanaka, S; Kubo, K; Sato, E; Konishi, S; Tanaka, H; Kameyama, Y; (1998). Electrochemotherapy Potentiation of Antitumor Effect of Cyclophosphamide by Local Electric Pulses on the Metastatic Lesion of Hamster Oral Fibrosarcoma. Presented at INABIS '98 - 5th Internet World Congress on Biomedical Sciences at McMaster University, Canada, Dec 7-16th. Available at URL http://www.mcmaster.ca/inabis98/cancer/maeda0671/index.html|
|© 1998 Author(s) Hold Copyright|