Invited Symposium: Molecular and Cellular Analysis of Dopamine and Serotonin Transporters



Materials & Methods


Discussion & Conclusion



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Role of the 5-HT Transporter in the Drug-Induced 'Carrier-Dependent' Release

Contact Person: Tiziana Mennini (tiziana@irfmn.mnegri.it)


Anderson B.B., Chen G., Gutman D.A., Ewing A.G.
Dopamine levels of two classes of vesicles are differentially depleted by amphetamine
Brain Res (1998) 788: 294-301

Cinquanta M., Ratoviski T., Crespi D., Gobbi M., Mennini T.,Simantov R.
Carrier-mediated serotonin release induced by d-fenfluramine: studies with human neuroblastoma cells transfected with a rat serotonin transporter
Neuropharmacol (1997) 36: 803-809

Crespi D., Mennini T., Gobbi M.
Carrier-dependent and Ca2+-dependent 5-HT and dopamine release induced by (+)amphetamine, 3,4-methylendioxymethamphetamine, p-chloroamphetamine and (+)fenfluramine
Br J Pharmacol (1997) 121: 1735-1743

Gobbi M., Frittoli E., Mennini T., Garattini S.
Releasing activities of d-fenfluramine and fluoxetine on rat hippocampal synaptosomes preloaded with [3H]serotonin
Naunyn-Schmiedeberg's Arch Pharmacol (1992) 345: 1-6

Gobbi M., Frittoli E., Uslenghi A., Mennini T.
Evidence of an exocytotic-like release of [3H]-5-hydroxytryptamine induced by d-fenfluramine in rat hippocampal synaptosomes
Eur J Pharmacol (1993) 238: 9-17

Jones S.R., Gainetdinov R.R., Wightman R.M., Caron M.G.
Mechanism of amphetamine action revealed in mice lacking the dopamine transporter
J Neurosci (1998) 18:1979-1986

Levi G., Raiteri M.
Carrier-mediated release of neurotransmitters
Trends Neurosci (1993) 16: 415-419

Reimann W., Schneider F.
Induction of 5-hydroxytryptamine release by tramadol, fenfluramine and reserpine
Eur J Pharmacol (1998) 349: 199-203

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<= Discussion & Conclussions REFERENCES

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Gobbi, M; Dalla Valle, F; Ciapparelli, C; Mennini, T; (1998). Role of the 5-HT Transporter in the Drug-Induced 'Carrier-Dependent' Release. Presented at INABIS '98 - 5th Internet World Congress on Biomedical Sciences at McMaster University, Canada, Dec 7-16th. Invited Symposium. Available at URL http://www.mcmaster.ca/inabis98/simantov/gobbi0727/index.html
© 1998 Author(s) Hold Copyright