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Immunology & Immunological Disorders Poster Session






Abstract

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A Novel Anti-inflammatory Activity of Human Lysozyme: Modulation of Serum Complement Activation

Ogundele, M.O. (Dept. of Immunology, Gerog-August University Goettingen, Germany)

Contact Person: Michael O. Ogundele (mogundel@yahoo.com)


Abstract

Lysozyme is an ubiquitous enzyme found in most biological secretions and leucocytes. This study was aimed at investigating its interaction with other inflammatory mediators on mucosa surfaces, particularly the complement system. Lysozyme has been shown in the present study, to inhibit the haemolytic activity of serum complement in a dose-dependent fashion, when tested within the levels present in normal and inflammed breast-milk samples, and other mucosal secretions. This reprersents a new anti-inflammatory action of lysozyme in relation to the serum complement, and the exact mode of interaction need further studies.

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Poster Number PAogundele0178
Keywords: Complement system, lysozyme, anti-inflammatory


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Ogundele, M.O.; (1998). A Novel Anti-inflammatory Activity of Human Lysozyme: Modulation of Serum Complement Activation. Presented at INABIS '98 - 5th Internet World Congress on Biomedical Sciences at McMaster University, Canada, Dec 7-16th. Available at URL http://www.mcmaster.ca/inabis98/immunology/ogundele0178/index.html
© 1998 Author(s) Hold Copyright