Cell Biology Poster Session



Materials & Methods


Discussion & Conclusion



INABIS '98 Home Page Your Session Symposia & Poster Sessions Plenary Sessions Exhibitors' Foyer Personal Itinerary New Search

Regulation of ground squirrel Na+K+-ATPase activity by reversible phosphorylation during hibernation.

Contact Person: Justin MacDonald (jmacdona@ccs.carleton.ca)


  1. Flanigan JE, Withers PC, Fuery CJ, Guppy M (1993) Metabolic depression and Na+/K+ gradients in the aestivating Australian goldfields frog, Neobatrachus wilsmorei. J Comp Physiol, B163: 587-593.
  2. Buck LT, Hochachka PW (1993) Anoxic suppression of Na+- K+-ATPase and constant membrane potential in hepatocytes: support for channel arrest. Am J Physiol, 265: R1020-R1025.
  3. Staples JF, Hochachka PW (1997) Liver energy metabolism during hibernation in the golden mantled ground squirrel, Spermophilus lateralis. Can J Zool, 75: 1059-1065.
  4. Clausen T (1986) Regulation of active Na+/K+ transport in skeletal muscle. Physiol Rev, 66: 542-576.
  5. Frank CL, Storey KB (1995) The optimal depot fat composition for hibernation by golden-mantled ground squirrels (Spermophilus lateralis). J Comp Physiol, 164B: 536-542.
  6. Sayos J, Solsona C, Mallol J, Lluis C, Franco R (1994) Phosphorylation of adenosine in renal brush-border membrane vesicles by an exchange reaction catalysed by adenosine kinase. Biochem J, 297: 491-496.
  7. Helmerhorst E, Stokes GB (1980) Microcentrifuge desalting: a rapid, quantitative method for desalting small amount of protein. Anal Biochem, 104: 130-135.
  8. Crombie HJ, Bell MV, Tutler P (1996) Inhibition of sodium-plus-potassium-stimulated adenosine triphosphatase (Na+/K+-ATPase) by protein kinase C activators in the gills of Atlantic cod (Gadus morhua). Comp Biochem Physiol, B113: 765-772.
  9. Ekman P and Jager O (1993) Quantification of subnanomolar amounts of phosphate bound to seryl and threonyl residues in phosphoproteins using alkaline hydrolysis and malachite green. Anal Biochem, 214: 138-141.
  10. Glynn IM, Karlish S (1990) Occluded cations in active transport. Annu Rev Biochem., 59: 171-205.
  11. Boldyrev A, Kurella E (1996) Mechanism of oxidative damage of dog kidney Na/K-ATPase. Biochem Biophys Res Comm, 222: 483-487.
  12. Ewart HS, Klip A (1995) Hormonal regulation of the Na+K+-ATPase: mechanisms underlying rapid and sustained changes in pump activity. Am J Physiol, 269: C295-C311.
  13. Bertorello AM, Katz AI (1995) Regulation of Na+-K+ pump activity: pathways between receptors and effectors. News Physiol Sci, 10: 253-259.
  14. Ikomi-Kumm J, Monti M, Hanson A, Johansson BW (1994) Microcalorimetric study on myocardial metabolism in a hibernator and two nonhibernators at 20°C and 37°C. Cryobiology, 31: 133-143.
  15. Zhou Z, Willis JS (1989) Differential effects of cooling in hibernator and non-hibernator cells: Na permeation. Am J Physiol, 256: R49-R55.
  16. Willis JS (1986) Membrane transport at low temperature in hibernators and nonhibernators. In C. Heller, ed., Living in the Cold. Elsevier: New York, pp. 27-34.

Back to the top.

<= Discussion & Conclussions REFERENCES

| Discussion Board | Next Page | Your Poster Session |
MacDonald, J.A.; Storey, K.B.; (1998). Regulation of ground squirrel Na+K+-ATPase activity by reversible phosphorylation during hibernation.. Presented at INABIS '98 - 5th Internet World Congress on Biomedical Sciences at McMaster University, Canada, Dec 7-16th. Available at URL http://www.mcmaster.ca/inabis98/cellbio/macdonald0174/index.html
© 1998 Author(s) Hold Copyright