Cancer Poster Session



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Altered Expression of Estrogen Receptor Alpha Variant mRNAs Between Adjacent Normal Breast And Breast Tumor Tissues.

Contact Person: Etienne Leygue (eleygue@cc.umanitoba.ca)


1. Murphy LC, Leygue E, Dotzlaw H, Douglas D, Coutts A, Watson PH. 1997 Oestrogen receptor variants and mutations in human breast cancer. Ann Med 29:221-234.

2. Lu B, Leygue E, Dotzlaw H, Murphy LJ, Murphy LC, Watson PH. 1998 Estrogen receptor-beta mRNA variants in human and murine tissues. Mol Cell Endocrinol. 138:199-203.

3. Wang Y, Miksicek RJ. 1991 Identification of a dominant negative form of the human estrogen receptor. Mol Endocrinol. 5:1707-1715.

4. Desai A, Luqmani Y, Coope R, et al. 1997 Presence of exon 5 deleted oestrogen receptor in human breast cancer: functional analysis and clinical significance. Br J Cancer. 75:1173-1184.

5. Fuqua SAW, Fitzgerald SD, Chamness GC, et al. 1991 Variant human breast tumor estrogen receptor with constitutive transcriptional activity. Cancer Res. 51:105-109.

6. Chaidarun S, Alexander J. 1998 A tumor specific truncated estrogen receptor splice variant enhances estrogen stimulated gene expression. Mol Endocrinol, 12:1355-1366.

7. Leygue ER, Watson PH, Murphy LC. 1996 Estrogen receptor variants in normal human mammary tissue. J Natl Cancer Inst. 88:284-290.

8. Dotzlaw H, Alkhalaf M, Murphy LC. 1992 Characterization of estrogen receptor variant mRNAs from human breast cancers. Mol Endocrinol. 6:773-785.

9. Leygue E, Murphy LC, Kuttenn F, Watson PH. 1996 Triple primer polymerase chain reaction. A new way to quantify truncated mRNA expression. Am J Pathol. 148:1097-1103.

10. Erenburg I, Schachter B, Lopez RM, Ossowski L. 1997 Loss of an estrogen receptor isoform (ER-alpha deleted 3) in breast cancer and the consequences of its reexpression: interference with estrogen-stimulated properties of malignant transformation. Mol Endocrinol. 11:2004-2015.

11. Murphy LC, Hilsenbeck SG, Dotzlaw H, Fuqua SAW. 1995 Relationship of clone 4 estrogen receptor variant messenger RNA expression to some known prognostic variables in human breast cancer. Clin Cancer Res. 1:155-159.

12. Leygue E, Hall RE, Dotzlaw H, Watson PH, Murphy LC. Estrogen receptor variant mRNA expression in primary human breast tumors and matched lymph node metastases. Br J Cancer. In press.

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Leygue, E; Dotzlaw, H; Watson, PH; Murphy, LC; (1998). Altered Expression of Estrogen Receptor Alpha Variant mRNAs Between Adjacent Normal Breast And Breast Tumor Tissues.. Presented at INABIS '98 - 5th Internet World Congress on Biomedical Sciences at McMaster University, Canada, Dec 7-16th. Available at URL http://www.mcmaster.ca/inabis98/cancer/leygue0756/index.html
© 1998 Author(s) Hold Copyright