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Immunology & Immunological Disorders Poster Session






Abstract

Introduction

Materials & Methods

Results

Discussion & Conclusion

References




Discussion
Board

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Bactericidal Activity of Human Milk Complement System


Contact Person: Michael O. Ogundele (mogundel@yahoo.com)


References

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4.Haffejee I.E.; Moosa A.;Windsor I. Circulating and breast-milk anti-rotaviral antibodies and neonatal rotavirus infection: a maternal-neonatal study. Ann-Trop-Paediatr. 1990; 10(1): 3-14.

5.Prentice A.; Watkinson M.; Prentice A.M.; Cole T.J.; Whitehead R,G. Breast-milk anti-microbial factors of rural Gambian mothers: Influence of stage of lactation and maternal plane of nutrition. Acta-Paediatr-Scand. 1984; 73(6): 796-802.

6.Prentice A.; Ewing G.; Roberts S.B. et al. The nutritional role of breast-milk IgA and lactoferrin. Acta- Paediatr-Scand. 1987; 76(4): 592-8.

7.Goldman-AS, Chheda S., Garofalo-R; Schmalstieg-FC Jr. Cytokines in human milk: properties and potential effects upon the mammary gland and the neonate. J. Mammary Gld. Biol. Neoplasia 1996; 1(3):251-58.

8.Nakajima S., Baba A.S., Tamura N. Complement system in Human Colostrum. Int. Archs. Allergy appl. Immun.. 1977; 54: 428-33.

9.Ballow-M; Fang-F; Good-RA; Day-NK. Developmental aspects of complement components in the newborn. The presence of complement components and C3 proactivator (properdin factor B) in human colostrum. Clin-Exp-Immunol. 1974; 18(2): 27-66

10.Lewis-Jones-DI; Lewis-Jones-MS; Connolly-RC; Lloyd-DC; West-CR. Sequential changes in the antimicrobial protein concentrations in human milk during lactation and its relevance to banked human milk. Pediatr-Res. 1985; 19(6): 561-5

11.Cole F.S.; Schneeberger E.E.; Lichtenberg N.A.; Colten H.R. Complement biosynthesis in human breast-milk macrophages and blood monocytes. Immunology. 1982; 46(2): 429-41.

12.Loos-M. The classical complement pathway: mechanism of activation of the first component by antigen-antibody complexes. Prog-Allergy. 1982; 30: 135-92

13.Gotze-O; Muller-Eberhard-HJ. The alternative pathway of complement activation. Adv-Immunol. 1976; 24: 1-35

14.Rainard P., Poutrel B., Caffin J.P. Assessment of hemolytic and bactericidal complement activities in normal and mastitic bovine milk. J. Dairy Science 1984; 67(3):614-9.

15.Avery V.M.; Gordon D.L. Antibacterial properties of breast-milk: requirements for surface phagocytosis and chemiluminiscence. Eur-J-Clin-Microbiol-Infect-Dis. 1991; 10(12): 1034-9.

16.Isaacs-CE; Kashyap-S; Heird-WC; Thormar-H. Antiviral and antibacterial lipids in human milk and infant formula feeds Arch-Dis-Child. 1990; 65(8): 861-4

17.Robinson-JE; Harvey-BA; Soothill-JF. Phagocytosis and killing of bacteria and yeast by human milk cells after opsonisation in aqueous phase of milk. Br-Med-J. 1978; 1(6125): 1443-5

18.Oppermann-M; Baumgarten-H; Brandt-E; Gottsleben-W; Kurts-C; Gotze-O. Quantitation of components of the alternative pathway of complement (APC) by enzyme-linked immunosorbent assays. : J-Immunol-Methods. 1990; 133(2): 181-90

19.Reiter-B; Brock-JH. Inhibition of Escherichia coli by bovine colostrum and post-colostral milk. I. Complement-mediated bactericidal activity of antibodies to a serum susceptible strain of E. coli of the serotype O 111. Immunology. 1975; 28(1): 71-82

20.Adinolfi-M; Glynn-AA; Lindsay-M; Milne-CM. Serological properties of gamma-A antibodies to Escherichia coli present in human colostrum. Immunology. 1966; 10(6): 517-26

21.Mollnes T.E., Garred P., Bergseth G. Effect of time, temperature and anticoagulants on in vitro complement activation: Consequences for collection and preservation of samples to be examined for complement activation. Clin. Exp. Immuniol. 1988; 73:484-8.

22.Samuelson-KJ; Rupnow-JH; Froning-GW. The effect of lysozyme and ethylenediaminetetraacetic acid on Salmonella on broiler parts. Poult-Sci. 1985; 64(8): 1488-90

23.Yonemasu K:, Kitajima H., Tanabe S., Ochi T., Shinkai H. Effect of age on C1q and C3 levels in human serum and their presence in colostrum. Immunology. 1978; 35(3): 523-30

24.Kassim-OO; Afolabi-O; Ako-Nai-KA. et al. Immunoprotective factors in breast milk and sera of mother-infant pairs. Trop-Geogr-Med. 1986; 38(4): 362-6

25.Friedrich B. In Mikrobiologische Diagnostik, Friedrich Burkhardt (editor), Georg Thieme Verlag Stuttgart, Germany (publishers), 1992; pg 780.

26.Kjiilstra A., Jeurissen S.H.M. Modulation of classical C3 convertase complement by tear lactoferrin. Immunology 1982; 47:263-70.

27.Russell-MW; Reinholdt-J; Kilian-M. Anti-inflammatory activity of human IgA antibodies and their Fab alpha fragments: inhibition of IgG-mediated complement activation. Eur-J-Immunol. 1989; 19(12): 2243-9

28.Hakulinen J., Meris S. Shedding and enrichment of the glycolipid-anchored complement lysis inhibitor protectin (CD59) into milk fat globules. Immunology 1995; 85(3):495-501.

29.Moffatt B.E., Sim R.B. Complement factor H and related proteins in human body fluids. Immunology 1995; 86(Suppl):162(Abstract)

30.Rainard P., Poutrel B. Deposition of complement components on Streptococcus agalactiae in bovine milk in the absence of inflammation. Infect. Immun. 1995; 63(9):3422-7.

31.Hernandez J., Lemons P., Lemons J.Todd J. (1979) Effect of storage processes on the bacterial growth-inhibitory activity of human breast milk. Pediatrics 63(4):597-601.

32.Reynolds G.J., Lewis-Jones D.I., Isherwood D.M., Meade H.J., Brown B.J., Fitzgerald T.S. A simplified system of human milk banking. Early Hum. Dev. 1982; 7(3):281-92.

33.Holmgren J., Hanson L.A., Carlson B, Lindblad B.S., Rahimtoola J. Neutralizing antibody against E. coli and V. cholera enterotoxins in human milk from a developing country. Scand. J. immunol. 1976; 5(6-7):867-71.

34.Yoshioka-H; Iseki-K; Fujita-K. Development and differences of intestinal flora in the neonatal period in breast-fed and bottle-fed infants. Pediatrics. 1983; 72(3): 317-21

35.Prentice-A; Prentice-AM; Lamb-WH. Mastitis in rural Gambian mothers and the protection of the breast by milk antimicrobial factors. Trans-R-Soc-Trop-Med-Hyg. 1985; 79(1): 90-5

36.Prentice-A; Watkinson-M; Prentice-AM; Cole-TJ; Whitehead-RG. Breast-milk antimicrobial factors of rural Gambian mothers. II. Influence of season and prevalence of infection. Acta-Paediatr-Scand. 1984; 73(6): 803-9

37.Ford-JE; Law-BA; Marshall-VM; Reiter-B. Influence of the heat treatment of human milk on some of its protective constituents. J-Pediatr. 1977; 90(1): 29-35

38.Goldman-AS The immune system of human milk: antimicrobial, antiinflammatory and immunomodulating properties. Pediatr-Infect-Dis-J. 1993 Aug; 12(8): 664-71

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<= Discussion & Conclussions REFERENCES

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Ogundele, M.O.; (1998). Bactericidal Activity of Human Milk Complement System. Presented at INABIS '98 - 5th Internet World Congress on Biomedical Sciences at McMaster University, Canada, Dec 7-16th. Available at URL http://www.mcmaster.ca/inabis98/immunology/ogundele0172/index.html
© 1998 Author(s) Hold Copyright