INABIS '98 - Involvement of Central Histamine in Amygdaloid Kindled Seizures in Rats

Invited Symposium: Neuronal Histamine Systems and Behavior

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Involvement of Central Histamine in Amygdaloid Kindled Seizures in Rats

Contact Person: Chiaki Kamei (kamei@pheasant.pharm.okayama-u.ac.jp)

Discussion and Conclusion

From the present study, it was found that histaminergic mechanisms play a suppressive role in amygdaloid kindled seizures through postsynaptic H₁-receptors. Presynaptic H₃-receptor is also involved in inhibiting amygdaloid kindled seizures.

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Kamei, C.; (1998). Involvement of Central Histamine in Amygdaloid Kindled Seizures in Rats. Presented at INABIS '98 - 5th Internet World Congress on Biomedical Sciences at McMaster University, Canada, Dec 7-16th. Invited Symposium. Available at URL http://www.mcmaster.ca/inabis98/huston/kamei0281/index.html