Dermatology Poster Session
Filosa, G (Division of Dermatology, A. Murri Hospital, Jesi, Italy)
Pachydermodactyly is a rare non-inflammatory bulbous swelling involving the dorsal and lateral surfaces of the fingers at the level of proxymal phalanges and interphalangeal joints. It was first described by Bazex el al. in 1973. It affects almost exclusively young males, but a few females have been reported. Generally the second, third and fourth fingers are affected bilaterally. Only four cases of pachydermodactyly localized to one finger have been reported. It is an acquired disease. In the majority of cases aetiology is unknown, but several hypotheses take into account repeated trauma, sometimes in the background of neurotic behaviour. Differential diagnosis is mainly made with knuckle pads, post-traumatic callosities, foreign-body granulomas, fibromas, infantile digital fibromatosis, rheumatoid and pseudo-rheumatoid nodules, arthritis, pachydermoperiostosis and proteus syndrome. A 22-year-old man presented with a 10-year history of asymptomatic persistent symmetrical swellings on the lateral and medial aspects of fingers II - III bilaterally. No family history of similar diseases, nor history of trauma was recorded. X-rays of the hands showed only soft tissue swellings. Histopathologic examination of a biopsy specimen revealed hyperkeratosis, hypergranulosis overlying a markedly thickened dermis, consisting of increased collagen bundles sometimes haphazardly arranged, slight proliferation of blood vessels, increased number of fibroblasts and perivascular lymphocytic infiltrate.
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|Bugatti, L; Filosa, G; (1998). Pachydermodactyly. A Case Report.. Presented at INABIS '98 - 5th Internet World Congress on Biomedical Sciences at McMaster University, Canada, Dec 7-16th. Available at URL http://www.mcmaster.ca/inabis98/dermatology/bugatti0112/index.html|
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