Poster
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RESULTS AND DISCUSION
By means of ANOVA similitude among the rats weight was demonstrated, before and after treatment.
VARIANCE ANALYSIS OF WEIGHT MEANS AT THE THIRD DAY OF THE EXPERIMENT
| GROUPS | MEAN | n |
| I | 230.200 | 24 |
| II | 225.179 | 24 |
| III | 228.513 | 24 |
| IV | 225.687 | 23 |
| V | 225.088 | 24 |
| GREAT MEAN | 226.944 | 119 |
| VARIATION SOURCE |
SQUARES SUM |
fd | MEAN SQUARE |
FCALC | P |
| GROUPS | 507.295 | 4 | 126.824 | 0.331 | 0.8568 |
| RESIDUAL | 43711.638 | 114 | 383.435 | ||
| TOTAL | 44218.933 | 118 |
ANOVA of damaged cells means showed no differences after treatment.
Factorial Correspondence analysis shows that only necrosis and damaged cells percentage are the prevalent endpoints.
CORRESPONDENCE FACTORIAL ANALYSIS
| ENDPOINTS ROW SUMS DIMENSIONS |
||||
| 1 2 3 | ||||
| Microvacuolar Esteatosis |
0.702 | 0.000 |
0.560 |
0.141 |
| Macrovacuolar Esteatosis |
1.206 | 0.104 |
0.485 |
0.618 |
| Necrosis | 1.251 | 0.835 |
0.307 |
0.110 |
| % damaged cells | 1.487 | 0.863 |
0.348 |
0.278 |
| Mean | 1.162 | 0.457 |
0.425 |
0.286 |
MANOVA shows significative differences between necrosis and damaged cells.
Plotting the mean values for treatment, group III (IFN 6CH) was found to have more variations.
MULTIPLE VARIANCE ANALYSIS
| Endpoint | F | p |
| Microvacuolar esteatosis | 2.244577 | 0.68568 |
| Macrovacuolar esteatosis | 0.986891 | 0.417693 |
| Necrosis | 3.506558 | 0.009718 |
| % damaged cells | 3.756407 | 0.006577 |
Statistic analysis of necrosis and cell damage shows group V (IFN 30CH) as the less damaged, possibly by protective effect of homeopathic substance.
NECROSIS DEGREE DUE TO CCI4 IN DIFFERENT EXPERIMENTAL GROUPS
DEGREE |
GROUP |
TOTAL |
||||
I |
II |
III |
IV |
V |
||
I |
4 |
8 |
4 |
7 |
12 |
35 |
II |
18 |
12 |
5 |
10 |
6 |
51 |
III |
2 |
4 |
15 |
6 |
6 |
33 |
TOTAL |
24 |
24 |
24 |
24 |
24 |
119 |
Chi square test shows significative differences between necrosis among the groups I and II, and I and V; being for group V the best results and for group III the worst. This leads to conclude that there is an additional toxicity of alcohol, which is not avoided with IFN protection in group III, and possible protection greater than all others in group VI.
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