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Immunology & Immunological Disorders Poster Session






Abstract

Introduction

Materials & Methods

Results

Discussion & Conclusion

References




Discussion
Board

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New Insights into the Role of Milk Fat Globule Membrane in the Sequestration of Particulate Antigens: Interactions with the Complement System


Contact Person: Michael O. Ogundele (mogundel@yahoo.com)


References

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2. Avery V.M.; Gordon D.L. (1991) Antibacterial properties of breast-milk: requirements for surface phagocytosis and chemiluminiscence. Eur J Clin Microbiol Infect Dis. 10(12): 1034-9.

3. Ballow-M; Donshik-PC; Mendelson-L (1985) Complement proteins and C3 anaphylatoxin in the tears of patients with conjunctivitis. J-Allergy-Clin-Immunol. 76(3): 473-6

4. Ballow M; Fang F; Good RA; Day NK (1974) Developmental aspects of complement components in the newborn. The presence of complement components and C3 proactivator (properdin factor B) in human colostrum. Clin Exp Immunol. 18(2): 257-66

5. Bhaskaram P; Reddy V (1981) Bactericidal activity of human milk leukocytes. Acta Paediatr Scand. 70(1): 87-90

6. Bitman-J; Wood-DL; Mehta-NR; Hamosh-P; Hamosh-M (1983) Lipolysis of triglycerides of human milk during storage at low temperatures: a note of caution. J-Pediatr-Gastroenterol-Nutr. 2(3): 521-4

7. Bjöksten B., Burman L.G., De Chateau P., Fredrikzon B.O., Gothefors L., Hernell O. (1980) Collecting and banking human milk: to heat or not to heat. British Medical Journal 281:765-9.

8. Buchheim-W; Welsch-U; Huston-GE; Patton-S (1988) Glycoprotein filament removal from human milk fat globules by heat treatment. Pediatrics. 81(1): 141-6

9. Cole F.S.; Schneeberger E.E.; Lichtenberg N.A.; Colten H.R. (1982) Complement biosynthesis in human breast-milk macrophages and blood monocytes. Immunology. 46(2): 429-41.

10. Cole LJN; Kluepfel D; Lusena CV. (1959) Freezing damage to bovine cream indicated by release of enzymes. Can J Biochem Physiol 37:821-7.

11. Crago SS; Prince SJ; Pretlow TG; McGhee JR; Mestecky J (1979) Human colostral cells. I. Separation and characterization. Clin Exp Immunol. 38(3): 585-97

12. France G.L.; Marmer D.J.; Steele R.W. (1980) Breast-feeding and Salmonella infection. Am J Dis Child. 134(2): 147-52.

13. Franke-WW; Heid-HW; Grund-C; Winter-S; Freudenstein-C; Schmid-E; Jarasch-ED; Keenan-TW (1981) Antibodies to the major insoluble milk fat globule membrane-associated protein: specific location in apical regions of lactating epithelial cells. J-Cell-Biol. 89(3): 485-94

14. Friedrich Burkhardt (1992) in Mikrobiologische Diagnostik, Friedrich Burkhardt (editor), Georg Thieme Verlag Stuttgart, Germany (publishers), pg 780.

15. Fukuoka Y; Nielsen LP; Hugli TE (1989) Characterization of receptors to the anaphylatoxins on isolated cells. Dermatologica.; 179 Suppl 1: 35-40 16. Goldman-AS; Thorpe-LW; Goldblum-RM; Hanson-LA (1986) Anti-inflammatory properties of human milk. Acta-Paediatr-Scand. 75(5): 689-95

17. Gotze-O; Muller-Eberhard-HJ (1976) The alternative pathway of complement activation. Adv-Immunol. 24: 1-35

18. Haffejee I.E.; Moosa A.;Windsor I. (1990) Circulating and breast-milk anti-rotaviral antibodies and neonatal rotavirus infection: a maternal-neonatal study. Ann Trop Paediatr. 10(1): 3-14.

19. Hakulinen J; Meri S (1995) Shedding and enrichment of the glycolipid-anchored complement lysis inhibitor protectin (CD59) into milk fat globules. Immunology. 85(3): 495-501

20. Isaacs CE; Kashyap S; Heird WC; Thormar H (1990) Antiviral and antibacterial lipids in human milk and infant formula feeds Arch Dis Child. 65(8): 861-4

21. Jason JM; Nieburg P; Marks JS (1984) Mortality and infectious disease associated with infant-feeding practices in developing countries. Pediatrics. 74(4 Pt 2): 702-27

22. Lewis-Jones-DI; Lewis-Jones-MS; Connolly-RC; Lloyd-DC; West-CR (1985) Sequential changes in the antimicrobial protein concentrations in human milk during lactation and its relevance to banked human milk. Pediatr-Res. 19(6): 561-5

23. Loos-M (1982) The classical complement pathway: mechanism of activation of the first component by antigen-antibody complexes. Prog-Allergy. 30: 135-92

24. Mayer M.M. (1971) In Experimental Immunochemistry (2nd edition) Kabat E.A., Mayer M.M., editors. Charles C. Thomas, Publisher, Springfield, IL pp. 133-159.

25. Minta JO; Jezyk PD; Lepow IH (1976) Distribution and levels of properdin in human body fluids. Clin Immunol Immunopathol. 5(1): 84-90

26. Moffatt B.E., Sim R.B.(1995) Complement factor H and related proteins in human body fluids. Immunology 86(Suppl):162 (Abstract).

27. Mollnes T.E., Garred P., Bergseth G. (1988) Effect of time, temperature and anticoagulants on in vitro complement activation: Consequences for collection and preservation of samples to be examined for complement activation. Clin. Exp. Immuniol. 73:484-8.

28. Morgan O.S., Bankey J., Quash G.A. (1975) The effect of lactoferrin , an iron-binding protein on complement activity. West Indian Med. J. 24:46-54.

29. Nakajima S., Baba A.S., Tamura N (1977) Complement system in Human Colostrum. Int. Archs. Allergy appl. Immun.. 54: 428-33.

30. Oppermann-M; Baumgarten-H; Brandt-E; Gottsleben-W; Kurts-C; Gotze-O (1990) Quantitation of components of the alternative pathway of complement (APC) by enzyme-linked immunosorbent assays. : J-Immunol-Methods. 133(2): 181-90

31. Prentice A.; Ewing G.; Roberts S.B.; Lucas A.; MacCarthy A.; Jarjou L.M.; Whitehead R.G. (1987) The nutritional role of breast-milk IgA and lactoferrin. Acta Paediatr Scand. 76(4): 592-8.

32. Rainard P., Poutrel B. (1995) Deposition of complement components on Streptococcus agalactiae in bovine milk in the absence of inflammation. Infect. Immun. 63(9):3422-7.

33. Rainard P., Poutrel B., Caffin J.P. (1984) Assessment of hemolytic and bactericidal complement activities in normal and mastitic bovine milk. J. Dairy Science 67(3):614-9.

34. Reiter B; Brock JH (1975) Inhibition of Escherichia coli by bovine colostrum and post-colostral milk. I. Complement-mediated bactericidal activity of antibodies to a serum susceptible strain of E. coli of the serotype O 111. Immunology. 28(1): 71-82

35. Rudloff HE;; Goldman AS, Chheda S., Garofalo R Schmalstieg FC Jr; (1996) Cytokines in human milk:properties and potential effects upon the mammary gland and the neonate. J. Mammary gld. Biol. Neoplasisa. 1(3):251-258.

36. Russell-MW; Reinholdt-J; Kilian-M (1989) Anti-inflammatory activity of human IgA antibodies and their Fab alpha fragments: inhibition of IgG-mediated complement activation. Eur-J-Immunol. 19(12): 2243-9

37. Schroten H; Hanisch FG; Plogmann R; Hacker J; Uhlenbruck G; Nobis-Bosch R; Wahn V (1992) Inhibition of adhesion of S-fimbriated Escherichia coli to buccal epithelial cells by human milk fat globule membrane components: a novel aspect of the protective function of mucins in the nonimmunoglobulin fraction. Infect-Immun. 60(7): 2893-9

38. Schroten H; Uhlenbruck G; Hanisch FG; van Mil A (1987) [Varying rates of phagocytosis of human blood monocytes and breast milk macrophages: effect of intralipid and milk fat globules] Unterschiedliche Phagozytoserate menschlicher Blutmonozyten und Muttermilchmakrophagen: Einfluss von Intralipid und Milchfettkügelchen. Monatsschr Kinderheilk. 135(1): 36-40

39. Welsch-U; Schumacher-U; Buchheim-W; Schinko-I; Jenness-P; Patton-S (1990) Histochemical and biochemical observations on milk-fat-globule membranes from several mammalian species. Acta-Histochem-Suppl. 40: 59-64

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<= Discussion & Conclussions REFERENCES

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Ogundele, M.O.; (1998). New Insights into the Role of Milk Fat Globule Membrane in the Sequestration of Particulate Antigens: Interactions with the Complement System. Presented at INABIS '98 - 5th Internet World Congress on Biomedical Sciences at McMaster University, Canada, Dec 7-16th. Available at URL http://www.mcmaster.ca/inabis98/immunology/ogundele0176/index.html
© 1998 Author(s) Hold Copyright