Neuropharmacology Poster Session

Pinealectomy and PHNO

Dave Kennaway


This is an interesting study.  I have been fascinated by your original observations for some time and I am glad that you are back studying the phenomenon again.  Do you intend attempting suprachiasmatic nucleus destruction in rats infused with PHNO?  I suspect that the tolerance sensitisation is occurring at a site innervated by efferents from the SCN.  The tracing literature should give you some clues where to look further.

Dave Kennaway

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