Signal Transduction in Endothelium: Mechano-Sensing, Ion Channels and Intracellular Calcium

Klaus Groschner paper:

Bernd Nilius

To Klaus Groschner: Do you have any idea why the trunctaed trp3 disrupts the activation of a non-selective cation channel? We were not able to verify that trp3, when overexpressed was store dependent? Have you any explanation? Did you try to transfect the cells woth anti-sense trp3 ? Any result?
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