Hypertension I: Structure of Small Arteries in Hypertension

Functional alterations in rat basilar artery induced by chronic inhibition of nitric oxide synthase (NOS). Are they related to vascular remodeling?

silvia arribas

Dr. Mulvany,

We have observed that L-NAME treatment increased adventitial cell
number, likely fibroblasts and macrofages. The work of Luvara et al. which demonstrates inflamatory cell infiltration and iNOS induction in rat aorta after oral L-NAME treatement, provides possible explanation for the source of iNOS in our experiments.

Silvia Arribas

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