SERCA-Type of Calcium Pumps and Phospholamban

Re^2: Poster 338


Dr, Lompre:  Thanx for the response. akg
On Tue Dec 8, lompre anne-marie wrote
>On Sun Dec 6, grover wrote
>>Dr. Lompre:
>>  Very interesting results.  Did you examine the effects of agents such as angiotensin or endothelin or the effects of IP3?  Also, what happens to SERCA2b in these cells?

>we  used angiotensin to stimulate the IP3 cascade and got the same results than with ATP after 2 days in culture but in freshly isolated cells angiotensin was inactive probably because the receptor was altered by the dissociation.
>SERCA 2b was unaltered during culture.

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