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Invited Symposium






Abstract

Introduction

Materials & Methods

Results

Discussion & Conclusion

References




Discussion
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Development of Midbrain Dopamine Neurons: Role of Epigenetic Factors


Contact Person: Umberto di Porzio (diporzio@iigbna.iigb.na.cnr.it)


References

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  2. Nelson EL, Liang CL, Sinton CM, et al. (1996) Midbrain dopaminergic neurons in the mouse: computer-assisted mapping. J Comp Neurol, 369:361-371.
  3. Egan MF, Weinberger DR (1997) Neurobiology of schizophrenia. Curr Opin Neurobiol, 7:701-707.
  4. Swanson J, Castellanos FX, Murias M et al. (1998) Cognitive neuroscience of attention deficit hyperactivity disorder and hyperkinetic disorder. Curr Opin Neurobiol, 8:263-271.
  5. Williams GV, Goldman-Rakic PS (1995) Modulation of memory fields by dopamine D1 receptors in prefrontal cortex. Nature, 376:572-575.
  6. Vallone D, Picetti R, Borrelli E (1999) The involvement of dopamine in various physiological functions: from drug addiction to cell proliferation. In “Dopaminergic Neuron Development” U. di Porzio, C. Perrone-Capano and R. Pernas-Alonso eds., Neuroscience Intellingence Unit, Landes Co Houston, USA. In press.
  7. Perrone-Capano C, Pernas-Alonso, R, di Por zio, U. (1999) Development of midbrain dopaminergic neurons. In “Dopaminergic Neuron Development” U. di Porzio, C. Perrone-Capano and R. Pernas-Alonso eds., Neuroscience Intellingence Unit, Landes Co Houston, USA. In press.
  8. Zetterstrom RH, Solomin L, Jansson L et al. (1997) Dopamine neuron agenesis in Nurr1-deficient mice. Science, 276:248-250.
  9. Smidt MP, van Schaick HS, Lanctot C et al. (1997) A homeodomain gene has highly restricted brain expression in mesencephalic dopaminergic neurons. Proc Natl Acad Sci U S A, 94:13305-13310.
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  11. Fiszman ML, Zuddas A, Masana MI et al. (1991) Dopamine synthesis precedes dopamine uptake in embryonic rat mesencephalic neurones. J Neurochem, 56, 392-399.
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  13. di Porzio U, Daguet MC, Glowinski J et al. (1980) Effect of striatal cells on in vitro maturation of mesencephalic dopaminergic neurones grown in serum-free conditions. Nature , 288:370-373.
  14. Perrone-Capano C, Tino A, di Porzio U. (1994) Target cells modulate dopamine transporter gene expression during brain development. Neuroreport, 5:1145-1148.
  15. di Porzio U, Zuddas A, Cosenza-Murphy DB et al. (1990) Early appearance of tyrosine hydroxylase immunoreactive neurones in the mesencephalon of mouse embryos. Int J Devl Neurosci, 8:523-532.
  16. Zuddas A, Corsini GU, Barker JL et al. Specific reinnervation of lesioned mouse striatum by grafted mesencephalic dopaminergic neurones. (1990) Eur J Neurosci, 3:72-85.
  17. di Porzio U, Rougon G, Novotny EA et al. (1987) Dopaminergic neurons from the mouse mesencephalon are enriched in culture through immunoreaction by ant i neural specific protein 4 monoclonal antibodies and flow cytometry. Proc. Natl. Acad. Sci. USA 84, 7334-7338.
  18. McLean JH, Shipley MT. (1988) Postmitotic, postmigrational expression of tyrosine hydroxylase in olfactory bulb dopaminergic neurons. J Neurosci, 8:3658-3669.
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  20. Bouvier MM, Mytilineou C. (1995) Basic fibroblast growth factor increases division and delays differentiation of dopamine precursors in vitro. J Neurosci, 15:7141-7149.
  21. Hynes M, Rosenthal A (1999) Specification of Dopaminergic Neurons: inductive Factors and Their Receptors. In “Dopaminergic Neuron Development” U. di Porzio, C. Perrone-Capano and R. Pernas-Alonso eds., Neuroscience Intellingence Unit, Landes Co Houston, USA. In press.
  22. Berger B., di Porzio U., Daguet M.C. et al . (1982) Long-term development of mesencephalic dopaminergic neurons of mouse embryos in dissociates primary cultures: morphological and histochemical characteristics. Neuroscience 7, 193-205.
  23. Amara SG, Arriza JL. (1993) Neurotransmitter transporters: three distinct gene families. Curr Opin Neurobiol, 3:337-344.
  24. Giros B, Jaber M, Jones SR et al. (1996) Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature, 379:606-612.
  25. Perrone Capano C, Tino A, Amadoro G et al. (1996) Dopamine transporter gene expression in rat mesencephalic dopaminergic neurones is increased by direct interaction with target striatal cells in vitro. Mol Brain Res, 39:160-166.
  26. Daguet MC, Di Porzio U, Prochiantz A et al. (1980) Release of dopamine from dissociated mesencephalic dopaminergic neurons in primary cultures in absence or presence of striatal target cells. Brain Res, 191:564-568.
  27. di Porzio U, Estenoz M. (1984) Positive control of target cerebellar cells on norepine phrine uptake in embryonic brainstem cultures in serum-free medium. Dev Brain Res, 16:147-157.
  28. Costantini LC, Isacson O (1999) Dopamine Neuron Grafts: Development and Molecular Biology. In “Dopaminergic Neuron Development” U. di Porzio, C. Perrone-Capano and R. Pernas-Alonso eds., Neuroscience Intellingence Unit, Landes Co Houston, USA. In press.
  29. Zuddas A, Corsini GU, Barker JL et al (1990). Specific reinnervation of lesioned mouse striatum by grafted mesencephalic dopaminergic neurons. Eur J Neurosci, 3:72-85.
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<= Discussion & Conclussions REFERENCES

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di Porzio, U; Perrone-Capano, C; Da Pozzo, P; (1998). Development of Midbrain Dopamine Neurons: Role of Epigenetic Factors. Presented at INABIS '98 - 5th Internet World Congress on Biomedical Sciences at McMaster University, Canada, Dec 7-16th. Invited Symposium. Available at URL http://www.mcmaster.ca/inabis98/
© 1998 Author(s) Hold Copyright