Surgery and Orthopedics Poster Session

Poster 670


Dr. Sakotnik:Hope you are enjoying the meeting.  Great poster.I found it fascinating that melatonin production in patients with CAD was decreased.  Correct me if I am wrong, I understood that at least in rats, the melatonin receptor binding also changes with the circadian rhythms.   Are there any data on the number of melatonin receptors in CAD.  If the decrease in plasma melatonin level were to reflect greater melatonin bound to the receptors, then the coclusions would be different from those if it occurred solely as a change in melatonin metabolism.

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