Pharmacology & Toxicology Poster Session

Poster 719


Dr. Bou: Great presentation.  Hope you have fun at the meeting. You conclude that Tg8 mutant mice obtained from C3H mice by disrupting the gene encoding monoamine oxidase-A - the serotonin (5-HT) degradation enzyme - showed very high 5-HT levels at birth and that is how the respiration rate in these rats was abnormal.  How selective is monoamine oxidase A for serotonin?  I understood that it was not very selective and if so how uniquely can you interpret your results?

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