Pharmacology & Toxicology Poster Session

Poster 656

Christopher M Tan

Dr. Cioni

Great poster.  Is there any homologue or comparable vasoactive peptides to urotensins in higher organisms?  Also, you've identified a role for NO production in these fish- which in turn, regulates the production of these urotensins- NO in higher organisms, seems to function primarily as a vasodilator, some reports of vasoconstrictor effects (associated with peroxinitrite, maybe), seems like a complex issue in the fish, not as linear.  Any thoughts of NOS fish knockouts?!?!?

Christopher Tan

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