Carbon Monoxide and Cardiovascular Function

Lingyun Wu

John Zhang

Dr. Wu,
Thank you for bring your work to our attention in this symposium. Zinc protophorphyrin, the structure of heme, produces elevation of intracellular calcium in smooth muscle cells. I would like to know more about the calcium modulation effect of protophorphyrin. Are there other metal protophorphyrin can be used in your study? such as Iron? Do they induce similar calcium elevation?
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