Hypertension III: Flow-Induced Vascular Remodeling

Dr. J. Tuttle (0776) Suppressed shear-mediated remodeling

Robert M.K.W. Lee

     One surprising finding in your study, is that there was no difference between SHR and WKY in the cross-sectional area of the media in both normal and collateral arteries.  This is different from our previous findings, and also from others who consistently found a larger medial CSA in the SHR than WKY, even in very young animals.  What was the age of these animals, and how were the vessels prepared for morphometric measurements?

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