Hypertension I: Structure of Small Arteries in Hypertension

Dr. Lehoux (0704

M.J. Mulvany

Dr. Lehoux,

Thank you for your summary of your interesting experiments.  What mechanisms could be responsible for the apparent differences in the pathways used by steady and pulsatile stretches.  Is it because genistein-sensitive pathways are downregulated by steady stretch, while herbimycin-sensitive pathways require time to be turned on?

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