Hypertension I: Structure of Small Arteries in Hypertension

Dr. Arribas (0145)

Robert M.K.W. Lee

I am confused.  Can you explain how iNOS induction due to treatment with L-NAME can cause 5-HT hyperreactivity?  You have stated that 5-HT hyperreactivity can be explained by the deficiency of NO to counteract the 5-HT contractions.  Your experiments with L-arginine suggests that L-NAME induces iNOS, therefore there should be an increased local amount of NO.
[ Previous ] [ Next ] [ Index ]           Wed Dec 9