Iron Transport


Re: symposium 706

Paul Fox
foxp@cesmtp.ccf.org


On Fri Dec 4, grover wrote
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>Dr. Fox: Fascinating results.  Hope you are having fun at the meeting.  Since you suggest that ceruloplasmin may cause Fe entry or release, what is the source of energy for its transport or do you think that this is simply and Fe(2+?)-gradient driven pathway?
>
Grover:Thanks for the kind words. Pretreatment of cells with energy metabolism inhibitors blocks Cp-stimulated iron uptake, so we think the process requires energy, most likely in the form of ATP.
Paul Fox
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