Cell Biology Poster Session

Re: Poster 296

Stephen Brooks

On Sun Dec 6, grover wrote
>Dr. Brooks: Fascinating results.  Hope you are having fun at the meeting. I was really fascinated that PFK had a Q10 of 3.6.  Two questions: is it known what is in the PFK molecular structure which results in such a high Q10?  Is this the same PFK which is present in most mammalian cells or a different isozyme?  Finally, I am glad that this frog does not have to live in the hot weather.
Thanks for the comments.  We presume that the PFK either exists already in an altered state via phosphorylation to change its physical characteristics or that it must be a radically different isozyme of PFK.  PFK is known to be terribly sensitive to polymerization/depolymerization and temperature may have a significant
role in this process.  As to a PFK with a Q10 of 3.6 already existing -  I don't know of another PFK that has a Q10 in this range but most of the invertebrate PFKs have not been tested for temperature effects by themselves.  


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