Intracellular Traffic of Organelles

Specificity of PRD of dynamin

Leonard Foster

Dr. Hussain.  Very nice symposium you have presented here.  I wonder if you could comment on something I have noticed lately.  It seems like everybody and their dog has a protein that will bind dynamin via a PRD/SH3 interaction.  I have trouble believing that dynamin has so many endogenous partners.  Do you have any idea of the specificity of your intersectin for dynamin (I know if binds SJ but what other PRDs can it bind)?  And how do you rationalize so many different partners for dynamin?


Leonard Foster

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