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Gerry Wright & Eric Brown Gerry Wright and Eric Brown, biochemistry.

Gerry Wright and Eric Brown

Outwitting microbes by designing novel antibiotics is a key goal of biochemists Dr. Gerry Wright, Canada Research Chair in Molecular Studies of Antibiotics and Dr. Eric Brown, Canada Research Chair in Antimicrobial Research.

 

 

Working out of the new McMaster High Throughput Screening Laboratory – a $15 million facility which screens compounds against bacterial targets as well as anti-AIDS and anti-cancer targets – the researchers are searching for new routes to the design of truly novel antibiotics.

Brown says that only one new class of antibiotics has reached the clinic in the last 30 years, yet, during that same period, there has been an alarming increase of reports of “superbugs”with resistance to existing antibiotics. Their goal: to find new chinks in the armour of bacteria.

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