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Yingfui Li, biochemistry.
Yingfu Li
Call it Darwinian evolution in a test tube. As holder of a Canada
Research Chair in Directed Evolution of Nucleic Acids, Dr. Yingfu
Li, Biochemistry, is one of the first scientists worldwide to study
the creation of genetic material for use as enzymes to detect damaged
genes or destroy cancer cells.
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His laboratory focuses on creating and studying DNA with
interesting properties, such as the ability to chew up RNA
molecules or to disable disease-causing proteins.
Having created a variety of tiny DNA molecules with catalytic
abilities, his lab is using these tools in biomedical applications,
including bio-sensing, disease control and drug screening.
“Instead of relying on Mother Nature to supply us with
DNA or RNA molecules for our study, we create them in our
hands using test-tube evolution technologies on a time scale
of weeks. We then have a lot of fun in getting them to do
interesting things for us.”
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