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Christopher M Tan
ctan@julian.uwo.ca
Great poster. Is there any homologue or comparable vasoactive peptides to urotensins in higher organisms? Also, you've identified a role for NO production in these fish- which in turn, regulates the production of these urotensins- NO in higher organisms, seems to function primarily as a vasodilator, some reports of vasoconstrictor effects (associated with peroxinitrite, maybe), seems like a complex issue in the fish, not as linear. Any thoughts of NOS fish knockouts?!?!?
Regards,
Christopher Tan
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Thu Dec 10