Molecular Physiology of Sodium-Calcium Exchange


Re: (0412) Alternative splicing of the rat eye NCKX1

Jonathan Lytton
jlytton@ucalgary.ca


On Tue Dec 8, Paul J. Bauer wrote
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>Congratulation! This is very imprortant work. I wonder if all these alternative splice products are expressed in the rat photoreceptor. If yes, what is the frequency of expression of each splice form?

thanks, Paul. You are quite right - this is an interesting question, but we don't know the answer. By RT-PCR one would guess that they are ~equally expressed in RNA isolated from the eye. What does that mean in terms of photoreceptor expression or, perhaps even more importantly, distribution, we have no idea!
-Jonathan


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