Abstract

Introduction

Materials & Methods

Results

Discussion & Conclusion

References

Discussion
Board

Autologous PBPC are increasingly used to reconstitute hemopoisis after high dose chemotherapy. PBPC were collected in 152 patients, 49 of them were transplanted by PBPC only and 25 with combination of PBPC and bone marrow. The mean number collected mononuclear cells was 2.2x 10e8/kg, CD34+ cells 2.25x 10e6/kg, and CFU-GM 0,9x 10e4/kg. There were no significant differences between mobilization using G-CSF, GM-CSF or combination of both above mentioned. The efficacy of mobilization was lower in previously intensively pretreated children. Recovery of marrow functions after transplantation of PBPC was more rapid than the recovery that follows bone marrow transplantation.

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Poster Number PAnovotny0531
Keywords: pbpc collection, pbpc mobilization, transplantation